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Familial isolated dilated cardiomyopathy

ORPHA:154· ICD-10 I42.0

Definition

A rare familial cardiomyopathy characterized by the dilation of left ventricle and progressively impairing of systolic ventricular function, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic impairment. The disease may cause heart failure or arrhythmia. The disease is isolated when no additional atypical cardiac or extracardiac manifestations are present.

Prevalence
1-9 / 100 000
Inheritance
Autosomal dominant, Autosomal recessive, Mitochondrial inheritance, X-linked recessive
Age of onset
All ages