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Trehalase deficiency

ORPHA:103909· ICD-10 E74.3

Definition

A rare, genetic, intestinal disease characterized by osmotic diarrhea, abdominal pain and increased rectal flatulence after ingestion of trehalose, a disaccharide found mainly in mushrooms, due to intestinal trehalase deficiency. It occurs primarily in the Greenland population, although cases have also been reported elsewhere.

Prevalence
Unknown
Inheritance
Autosomal dominant
Age of onset
Adolescent, Adult