Alpha-heavy chain disease
ORPHA:100025· ICD-10 C88.3
Definition
A type of HCD characterized by the production of incomplete monoclonal alpha-heavy chains without associated light chains. Alpha-HCD is considered to be a subtype of immunoproliferative small intestinal disease (IPSID). The clinical presentation includes chronic diarrhea with evidence of malabsorption.
- Prevalence
- Unknown
- Age of onset
- Adolescent, Adult