Дискоїдний червоний вовчак
ORPHA:90281· ICD-10 L93.0· Discoid lupus erythematosus
Визначення(English summary)
A rare form of chronic cutaneous lupus erythematosus characterized by erythematous, scaly papules and plaques preferentially occurring on sun-exposed skin areas (scalp, face, and ears) and exhibiting follicular plugging, pigmentary changes, and central atrophy, scarring, and telangiectasia. Skin biopsy shows a perivascular and periadnexal lymphocytic infiltrate and involvement of the dermoepidermal junction with thickening of the basement membrane and vacuolar degeneration of the basal cells. A small percentage of patients may develop systemic lupus erythematosus.
- Поширеність
- 1-5 / 10 000
- Вік початку
- Adolescent, Adult, Childhood, Elderly