Первинний бічний склероз
ORPHA:35689· ICD-10 G12.2· Primary lateral sclerosis
Визначення(English summary)
Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production.
- Поширеність
- 1-9 / 100 000
- Успадкування
- Autosomal dominant, Autosomal recessive, Not applicable
- Вік початку
- Adult, Elderly