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Familial acute necrotizing encephalopathy

ORPHA:88619· ICD-10 G93.4

Definition

Familial acute necrotizing encephalopathy or ADANE is a potentially fatal neurological disease characterised by neuropathological lesions principally involving the brainstem, thalamus and putamen.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Adolescent, Adult, Childhood, Infancy