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Epidermolysis bullosa simplex with mottled pigmentation

ORPHA:79397· ICD-10 Q81.0

Definition

A rare, inherited, epidermolysis bullosa simplex characterized by neonatal or infantile onset of generalized blistering with mottled or reticulate brown pigmentation developing later. Blistering is often accompanied by mild nail dystrophy and focal palmoplantar keratoderma, and rarely by milia and mostly affects the limbs and trunk.

Prevalence
Unknown
Inheritance
Autosomal dominant
Age of onset
Infancy, Neonatal