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Hepatic veno-occlusive disease-immunodeficiency syndrome

ORPHA:79124· ICD-10 K76.5

Definition

A rare syndrome with combined immunodeficiency characterized by the association of severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, absent tissue plasma cells and hepatic veno-occlusive disease.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Infancy