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Congenital membranous nephropathy due to fetomaternal anti-neutral endopeptidase alloimmunization

ORPHA:69063· ICD-10 P96.0

Definition

A rare, congenital glomerular disease due to maternal anti-neutral endopeptidase (NEP) alloimmunization characterized by severe renal failure and nephrotic syndrome at birth, which rapidly improves in the first weeks of life.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Antenatal, Neonatal