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Autosomal dominant hereditary chronic pancreatitis

ORPHA:676· ICD-10 K86.1

Definition

A rare gastroenterologic disease characterized by recurrent acute pancreatitis and/or chronic pancreatitis in at least 2 first-degree relatives, or 3 or more second-degree relatives in 2 or more generations, for which no predisposing factors are identified. This rare inherited form of pancreatitis leads to irreversible damage to both exocrine and endocrine components of the pancreas.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Adolescent, Childhood