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Netherton syndrome

ORPHA:634· ICD-10 Q80.8

Definition

Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal