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Moebius syndrome

ORPHA:570· ICD-10 Q87.0

Definition

A very rare congenital cranial dysinnervation disorder characterized by unilateral or bilateral non progressive congenital facial palsy (VII cranial nerve) with impairments of ocular abduction (VI cranial nerve). It can also be associated with other cranial nerves palsies, orofacial anomalies and limb defects.

Prevalence
1-9 / 100 000
Inheritance
Autosomal dominant
Age of onset
Antenatal, Neonatal