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Familial hemophagocytic lymphohistiocytosis

ORPHA:540· ICD-10 D76.1

Definition

Familial Hemophagocytic lymphohistiocytosis (FHL) is a rare primary immunodeficiency characterized by a macrophage activation syndrome with an onset usually occurring within a few months or less common several years after birth.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Adolescent, Infancy