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Familial glucocorticoid deficiency

ORPHA:361· ICD-10 E27.1

Definition

Familial glucocorticoid deficiency (FGD) is a group of primary adrenal insufficiencies characterized clinically by neonatal hyperpigmentation, hypoglycemia, failure to thrive, and recurrent infections, and biochemically by glucocorticoid deficiency without mineralocorticoid deficiency.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Childhood, Infancy