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Absent tibia-polydactyly-arachnoid cyst syndrome

ORPHA:3328· ICD-10 Q87.5

Definition

A rare multiple congenital anomalies/dysmorphic syndrome characterized by absence/hypoplasia of tibia, postaxial polydactyly of the hands, pre and /or postaxial polydactyly of the feet and retrocerebellar arachnoid cyst. Bowing of the radius and ulna and syndactyly may also be present. Additional clinical features may include ventriculomegaly, cleft lip, diaphragmatic agenesis and malrotation of the colon. There have been no further descriptions in the literature since 1995.

Prevalence
<1 / 1 000 000
Inheritance
Unknown
Age of onset
Infancy, Neonatal