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Peripheral motor neuropathy-dysautonomia syndrome

ORPHA:2400· ICD-10 G60.8

Definition

A rare peripheral motor neuropathy characterized by distal, slowly progressive muscular weakness, childhood-onset amyotrophy, and autonomic dysfunction, manifesting as profuse sweating, cold-induced distal cyanosis, orthostatic hypotension, and esophageal achalasia. There have been no further descriptions in the literature since 1981.

Prevalence
<1 / 1 000 000
Inheritance
Unknown
Age of onset
Childhood