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Keratosis follicularis spinulosa decalvans

ORPHA:2340· ICD-10 Q82.8

Definition

Keratosis follicularis spinulosa decalvans is a rare genodermatosis occurring during infancy or childhood, predominantly affecting males, and characterized by diffuse follicular hyperkeratosis associated with progressive cicatricial alopecia of the scalp, eyebrows and eyelashes. Additional findings can include photophobia, corneal dystrophy, facial erythema, and/or palmoplantar keratoderma.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant, Autosomal recessive, X-linked recessive
Age of onset
Childhood