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Arthrogryposis multiplex congenita

ORPHA:1037· ICD-10 Q74.3

Definition

A group of disorders characterized by congenital limb contractures manifesting as limitation of movement of multiple limb joints at birth that is usually non-progressive and may include muscle weakness and fibrosis. This disorder is always associated with decreased intrauterine fetal movement which leads secondarily to the contractures.

Prevalence
1-9 / 100 000
Inheritance
Autosomal dominant, Autosomal recessive, Not applicable, X-linked recessive
Age of onset
Neonatal