Landau-Kleffner syndrome
ORPHA:98818· ICD-10 F80.3
Definition
A rare form of epileptic encephalopathy with spike-wave activation in sleep (EE-SWAS) characterized by various combinations of acquired cognitive, language, behavioral, and motor deficits associated with marked spike- and- wave activation in sleep. In Landau-Kleffner syndrome (LKS), receptive language is mainly affected, with an acquired auditory verbal agnosia.
- Prevalence
- 1-9 / 1 000 000
- Inheritance
- Autosomal dominant, Unknown
- Age of onset
- Childhood