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Hepatic veno-occlusive disease

ORPHA:890· ICD-10 K76.5

Definition

A rare vascular liver disease characterized by toxic injury to the hepatic sinusoidal capillaries that leads to obstruction of the small hepatic veins and sinusoids. Clinical manifestations include painful hepatomegaly, jaundice, and fluid retention that manifests by weight gain, edemas, and ascites.

Prevalence
Unknown
Inheritance
Not applicable
Age of onset
All ages