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Laron syndrome

ORPHA:633· ICD-10 E34.3

Definition

Laron syndrome is a congenital disorder characterized by marked short stature associated with normal or high serum growth hormone (GH) and low serum insulin-like growth factor-1 (IGF-I) levels which fail to rise after exogenous GH administration.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Infancy, Neonatal