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X-linked parkinsonism-spasticity syndrome

ORPHA:363654· ICD-10 G20

Definition

A rare, genetic, neurological disorder characterized by parkinsonian features (including resting or action tremor, cogwheel rigidity, hypomimia and bradykinesia) associated with variably penetrant spasticity, hyperactive deep tendon reflexes and Babinski sign.

Prevalence
<1 / 1 000 000
Inheritance
X-linked recessive
Age of onset
Adolescent, Adult