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Sternal cleft

ORPHA:2017· ICD-10 Q76.7

Definition

A rare idiopathic congenital thoracic malformation characterized by a sternal fusion defect, that can be complete or partial (either superior or inferior), that is usually asymptomatic in the neonatal period (apart from a paradoxical midline thoracic bulging) but that can lead to dyspnea, cough, frequent respiratory infections and increased risk of trauma-related injury to the heart, lungs and major vessels if left untreated.

Prevalence
1-9 / 100 000
Inheritance
Not applicable
Age of onset
Antenatal, Neonatal