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Cerebral proliferative angiopathy

ORPHA:692271

Definition

A rare arteriovenous malformation characterized by seizures, disabling headaches, and stroke-like symptoms with progressive neurological deficits due to a proliferative response to chronic parenchymal ischaemia. Normal brain parenchyma is interspersed throughout the vascular malformation. Hemorrhagic presentations are uncommon; however, when present, the risk of reccurence is higher in such patients than in those with classic cerebral arteriovenous malformation.

Prevalence
1-9 / 1 000 000
Age of onset
Adolescent, Adult, Childhood