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FLNC-related handgrip and calf weakness-distal myopathy

ORPHA:63273· ICD-10 G71.0

Definition

Distal myopathy with posterior leg and anterior hand involvement, also named distal ABD-filaminopathy, is a neuromuscular disease characterized by a progressive symmetric muscle weakness of anterior upper and posterior lower limbs.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Adolescent, Adult