Medulloblastoma
ORPHA:616· ICD-10 C71.6
Definition
A rare embryonic tumor of the neuroepithelial tissue characterized clinically by increased intracranial pressure and cerebellar dysfunction, with the most common presenting symptoms being headache, vomiting, and ataxia. The disease can be classified according to histological (classic, anaplastic, large-cell, or desmoplatic medulloblastoma, or medulloblastoma with extensive nodularity) and molecular criteria (WNT-activated, sonic-hedgehog-activated, group 3, group 4).
- Prevalence
- 1-9 / 1 000 000
- Inheritance
- Not applicable
- Age of onset
- All ages