Alexander disease
ORPHA:58· ICD-10 G93.8
Definition
A rare neurodegenerative disorder of the astrocytes comprised of two clinical forms: Alexander disease (AxD) type I and type II manifesting with various degrees of macrocephaly, spasticity, ataxia and seizures and leading to psychomotor regression and death.
- Prevalence
- Unknown
- Inheritance
- Autosomal dominant
- Age of onset
- All ages