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Neonatal scleroderma

ORPHA:398127· ICD-10 P83.8

Definition

A rare secondary neonatal autoimmune disease characterized by neonatal-onset of erythematous skin lesions with a linear appearance that gradually become indurated and hyperpigmented and progressively present skin atrophy. Positive serum antibodies (in particular antinuclear antibodies and/or rheumatoid factor) may be associated.

Prevalence
<1 / 1 000 000
Age of onset
Neonatal