Chronic granulomatous disease
ORPHA:379· ICD-10 D71
Definition
A rare primary immunodeficiency, mainly affecting phagocytes, which is characterized by an increased susceptibility to severe and recurrent bacterial and fungal infections, along with the development of granulomas.
- Prevalence
- 1-9 / 1 000 000
- Inheritance
- Autosomal recessive, X-linked recessive
- Age of onset
- Adolescent, Adult, Childhood, Infancy