Vogt-Koyanagi-Harada disease
ORPHA:3437· ICD-10 H20.8
Definition
A rare bilateral granulomatous panuveitis characterized by an acute phase with serous retinal detachments associated with neurological (meningitis) and auditory alterations which, in case of delayed (>3-4 weeks) or insufficient treatment, evolves into a chronic phase with chronic anterior uveitis and retinal atrophic lesions (Dalen-Fuchs nodules and sunset glow fundus) associated with dermatological alterations. The disease is marked by increased choroidal inflammatory activity.
- Prevalence
- Unknown
- Inheritance
- Multigenic/multifactorial
- Age of onset
- All ages