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Vogt-Koyanagi-Harada disease

ORPHA:3437· ICD-10 H20.8

Definition

A rare bilateral granulomatous panuveitis characterized by an acute phase with serous retinal detachments associated with neurological (meningitis) and auditory alterations which, in case of delayed (>3-4 weeks) or insufficient treatment, evolves into a chronic phase with chronic anterior uveitis and retinal atrophic lesions (Dalen-Fuchs nodules and sunset glow fundus) associated with dermatological alterations. The disease is marked by increased choroidal inflammatory activity.

Prevalence
Unknown
Inheritance
Multigenic/multifactorial
Age of onset
All ages