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Odontohypophosphatasia

ORPHA:247685· ICD-10 E83.3

Definition

A particular form of hypophosphatasia (HPP) characterized by reduced activity of unfractionated serum alkaline phosphatase, premature exfoliation of primary and/or permanent teeth and/or severe dental caries, in the absence of skeletal system abnormalities.

Prevalence
Unknown
Inheritance
Autosomal dominant, Autosomal recessive
Age of onset
Adolescent, Adult, Childhood, Infancy