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Atypical hemolytic uremic syndrome

ORPHA:2134· ICD-10 D59.3

Definition

A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction.

Prevalence
1-9 / 1 000 000
Inheritance
Autosomal dominant, Autosomal recessive, Not applicable
Age of onset
All ages