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Alternating hemiplegia of childhood

ORPHA:2131· ICD-10 G98

Definition

A rare neurological syndrome characterized by episodes of hemiplegia (alternating between the two sides of the body) or tetraplegia, and other accesses such as abnormal ocular movements, dystonia, and dysautonomia. Patients have permanent neurological impairment, variable degrees of intellectual disability, movement disorders, and psychiatric problems. Half of them present with epilepsy.

Prevalence
Unknown
Inheritance
Autosomal dominant, Not applicable
Age of onset
Infancy, Neonatal