O'Sullivan-McLeod syndrome
ORPHA:99965· ICD-10 G12.8
Definition
A rare acquired motor neuron disease characterized by an initial unilateral weakness in the intrinsic hand muscles that eventually spreads to the opposite limb (with an asymmetrical distribution) and that has a very slow progression of muscular atrophy over a 20 year period.
- Prevalence
- <1 / 1 000 000
- Age of onset
- Adult