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Mills syndrome

ORPHA:94091· ICD-10 G12.2

Definition

A rare, acquired motor neuron disease characterized by a slowly progressive, unilateral, ascending or descending hemiplegia, associated to unilateral or asymmetrical pyramidal signs and no sensory loss. It is a diagnosis of exclusion and controversy exists regarding whether the presence of bulbar symptoms, sphincter disturbances, fasciculations or cognitive manifestations characterize the disease.

Prevalence
1-9 / 1 000 000
Age of onset
Adolescent, Adult, Childhood, Elderly