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Acquired partial lipodystrophy

ORPHA:79087· ICD-10 E88.1

Definition

A rare acquired lipodystrophy characterized by bilateral, symmetrical lipoatrophy of the upper body (face, neck, arms, thorax and sometimes upper abdomen) with sparing of the lower extremities and cephalothoracic progression. The disease may be associated with low serum levels of C3 and presence of C3-nephritic factor.

Prevalence
Unknown
Inheritance
Multigenic/multifactorial, Not applicable
Age of onset
Adolescent, Adult, Childhood