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Rabson-Mendenhall syndrome

ORPHA:769· ICD-10 E34.8

Definition

A subtype of INSR-related severe insulin-resistance syndrome characterized by intrauterine and postnatal growth delay, short stature, acanthosis nigricans, dental, hair and nail abnormalities, facial dysmorphism, organomegaly and major hyperinsulinemia with dysglycemia.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Antenatal, Childhood, Infancy, Neonatal