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Transient predisposition to invasive pyogenic bacterial infection

ORPHA:70592· ICD-10 D84.8

Definition

Interleukin-1 receptor-associated kinase-4 (IRAK-4) deficiency is an immunodeficiency associated with increased susceptibility to invasive infections caused by pyogenic bacteria.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Childhood