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Intrahepatic cholestasis of pregnancy

ORPHA:69665· ICD-10 O26.6

Definition

Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile acid levels, and (iii) spontaneous relief of signs and symptoms within two to three weeks after delivery.

Prevalence
Unknown
Inheritance
Multigenic/multifactorial, Not applicable
Age of onset
Adult