Rowell syndrome

Definition

A rare rheumatologic disease characterized by combination of systemic or cutaneous lupus erythematosus with erythema multiform-like skin lesions and characteristic immunologic findings including speckled pattern of antinuclear antibody, presence of anti-Ro/SSA or anti-La/SSB antibodies or rheumatoid factor. Chilblains may also be present. Patients may present with fever, hair loss, photosensitivity, polyarthralgia, morning stiffness, fatigue, weight loss and oral ulcers. Middle-aged women are predominantly affected.