Acute promyelocytic leukemia
ORPHA:520· ICD-10 C92.4
Definition
An aggressive form of acute myeloid leukemia (AML), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells, and manifests with easy bruising, hemorrhagic diathesis and fatigue.
- Prevalence
- Unknown
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Childhood, Elderly