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Vibratory urticaria

ORPHA:493342· ICD-10 L50.4

Definition

Vibratory urticaria is a rare, genetic urticaria characterized by the development of localized, short-lasting (resolving within 1 hour), pruritic, erythematous, edematous hives in response to repetitive frictional or vibratory stimulation of the skin, which in some cases is accompanied by facial flushing, headache or the sensation of a metallic taste. Concomitant local mast cell degranulation and increased histamine serum levels are additional typical findings.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
All ages