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Pure autonomic failure

ORPHA:441· ICD-10 G90.8

Definition

A rare sporadic neurodegenerative disease characterized by slowly progressive symptoms of orthostatic hypotension (OH), and other symptoms of generalised dysautonomia related to the impairment of the sympathetic component of the autonomic nervous system.

Prevalence
1-9 / 1 000 000
Inheritance
Not applicable
Age of onset
Adult, Elderly