Malignant hyperthermia of anesthesia
ORPHA:423· ICD-10 T88.3
Definition
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely, to stresses such as vigorous exercise and heat.
- Prevalence
- Unknown
- Inheritance
- Autosomal dominant
- Age of onset
- All ages