Graft versus host disease
ORPHA:39812· ICD-10 T86.0
Definition
A rare immune disease characterized by donor-derived immune cells, primarily T cells, recognizing the recipient's tissues as foreign and mounting an immune response against them. It is a significant complication following allogeneic hematopoietic cell transplantation (alloHCT). Graft versus host disease (GVHD) is classified into acute (aGVHD) and chronic (cGVHD) forms.
- Prevalence
- 1-9 / 100 000
- Inheritance
- Not applicable
- Age of onset
- All ages