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Multicentric osteolysis-nodulosis-arthropathy spectrum

ORPHA:371428· ICD-10 M89.5

Definition

A rare systemic or rheumatologic disease characterized by peripheral osteolysis (especially carpal and tarsal bones), interphalangeal joint erosions, subcutaneous fibrocollagenous nodules, facial dysmorphism, and a wide range of associated manifestations.

Prevalence
Unknown
Inheritance
Autosomal recessive
Age of onset
Childhood, Infancy