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Stiff person spectrum disorder

ORPHA:3198· ICD-10 G25.8

Definition

A rare neurological disorder comprising fluctuating trunk and limb stiffness, painful muscle spasms, task-specific phobia related to walking, an exaggerated startle response, and often ankylosing deformities such as fixed lumbar hyperlordosis.

Prevalence
1-9 / 1 000 000
Inheritance
Not applicable
Age of onset
Adolescent, Adult, Childhood, Elderly, Infancy