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Young-onset Parkinson disease

ORPHA:2828· ICD-10 G20

Definition

A rare parkinsonian disorder characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most forms of this disease.

Prevalence
1-5 / 10 000
Inheritance
Autosomal recessive
Age of onset
Adult