Autoimmune hemolytic anemia, cold type

Definition

Cold autoimmune hemolytic anemia comprises two types of autoimmune hemolytic anemia (AIHA) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30 °C): cold agglutinin disease (CAD), which is the more common, and paroxysmal cold hemoglobinuria (PCH).