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Seborrhea-like dermatitis with psoriasiform elements

ORPHA:168606· ICD-10 L21.8

Definition

A rare, genetic, epidermal disorder characterized by a chronic, diffuse, fine, scaly erythematous rash on the face (predominantly the chin, nasolabial folds, eyebrows), around the earlobes and over the scalp, associated with hyperkeratosis over elbows, knees, palms, soles and metacarpophalangeal joints, in the absence of associated rheumatological or neurological disorders. Cold weather, emotional stress and strenuous physical activity may exacerbate symptoms.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal dominant
Age of onset
Childhood